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BPSL1774 BPSL1774 purL purL BPSL1776 BPSL1776 purC purC purF purF purH purH BPSL1779 BPSL1779 purE purE purK purK purM purM BPSL2622 BPSL2622
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSL1774Putative siderophore biosynthesis related protein; Similar to Pseudomonas aeruginosa pyoverdine synthetase F PvdF SWALL:P72114 (EMBL:U07359) (275 aa) fasta scores: E(): 2.5e-78, 73.89% id in 272 aa, and to Burkholderia cepacia ornibactin synthetase F PvdF SWALL:Q9F479 (EMBL:AF013993) (279 aa) fasta scores: E(): 9.5e-68, 67.64% id in 272 aa. (279 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.974
BPSL1776
Similar to Pseudomonas aeruginosa L-ornithine 5-monooxygenase PvdA or Pvd-1 or pa2386 SWALL:PVDA_PSEAE (SWALL:Q51548) (443 aa) fasta scores: E(): 2.3e-63, 48.01% id in 454 aa, and to the C-terminal region of Burkholderia cepacia L-ornithine 5-monooxygenase PvdA SWALL:PVDA_BURCE (SWALL:O51940) (444 aa) fasta scores: E(): 4.6e-124, 77.85% id in 411 aa.
 
  
 0.935
purC
Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa.
  
 
 0.873
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.859
purH
Similar to Escherichia coli bifunctional purine biosynthesis protein [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (aicar transformylase); IMP cyclohydrolase (EC 3.5.4.10) (inosinicase) (IMP synthetase) (atic)] PurH or b4006 SWALL:PUR9_ECOLI (SWALL:P15639) (529 aa) fasta scores: E(): 1.5e-122, 62.28% id in 525 aa, and to Ralstonia solanacearum probable bifunctional: phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase transmembrane protein rsc0504 or rs05018 SWALL:Q8Y232 (EMBL:AL646059) (524 aa) fasta scores: E(): 4.6e-170 [...]
  
 
 0.858
BPSL1779
Putative siderophore biosynthesis related ABC transport protein; Similar to Pseudomonas aeruginosa pyoverdine synthetase E PvdE SWALL:Q51340 (EMBL:U07359) (548 aa) fasta scores: E(): 1.4e-59, 37.7% id in 557 aa, and to Pseudomonas syringae ATP-binding protein SyrD SWALL:SYRD_PSESY (SWALL:P33951) (566 aa) fasta scores: E(): 7.7e-51, 36.92% id in 539 aa.
 
  
 0.855
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.852
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.852
purM
Similar to Escherichia coli phosphoribosylformylglycinamidine cyclo-ligase PurM or PurG or b2499 SWALL:PUR5_ECOLI (SWALL:P08178) (344 aa) fasta scores: E(): 2.9e-78, 59.76% id in 343 aa, and to Ralstonia solanacearum probable phosphoribosylformylglycinamidine cyclo-ligase PurM or rsc2623 or rs00927 SWALL:Q8XW52 (EMBL:AL646071) (353 aa) fasta scores: E(): 1.9e-108, 81.21% id in 346 aa, and to Neisseria meningitidis putative phosphoribosylformylglycinamidine cyclo-ligase PurM or nma1421 SWALL:Q9JUA2 (EMBL:AL162755) (344 aa) fasta scores: E(): 7.4e-90, 68.73% id in 339 aa.
  
  
 0.851
BPSL2622
Hypothetical protein; No significant database matches.
  
     0.764
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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